using wildcards in and and an IN in a Where clause

I have 500 strings that i need to do a wildcard on.
example:  PARTNUM LIKE '%abcde%'
but i have to find 500 different PartNums.
Obviosly i can't do  IN ('%abcde%','%rthyg%','%UYTR%')
How can i search for my list of partnums in on